Towards Healthcare

AnalytiChem Launches Complete CONOSTAN Standards Range for ASTM D3606 Benzene/Toluene Testing

Category: Health Published Date: 18 August 2026

AnalytiChem expanded CONOSTAN into ASTM D3606 fuel speciation with standardized calibration curve kits and check standards aligned to both method procedures.

AnalytiChem, a dealer of specialty chemicals, reference standards, and laboratory consumables, has announced the availability of a novel line of CONOSTAN-branded gas chromatography (GC) standards intended to support the full analytical workflow for ASTM D3606, the standard test processes used to regulate benzene and toluene content in spark-ignition engine fuels.

The AnalyticChem website states that "for nearly 50 years, CONOSTAN has been recognized as the benchmark brand in oil standards and certified reference materials for the petroleum and fuels industries. Laboratories, refineries, and research teams worldwide trust the name because it consistently delivers accuracy, stability, and confidence."

For laboratories running D3606, the announcement addresses a familiar pain point: sourcing a coherent set of standards, from calibration via system-suitability checks, without having to piece together materials from multiple vendors with differing certification solutions. The novel 19-product range involves calibration curve kits and check standards for both the A and B technologies pertinent to the method, along with straight internal standards and system-suitability services.

Why This Matters to GC Analysts

Benzene's status as a regulated carcinogen, along with the role aromatic content plays in both emissions' performance and fuel quality, means D3606 output carries substantial government and operational weight for refiners confirming compliance, mixture optimizing gasoline formulations, and third-party laboratories running routine QC. As with any GC processes reliant on internal standardization, the precision of D3606 output depends heavily on variables that go beyond the calibration curve itself: peak resolution among benzene, toluene, and coeluting matrix components; the integrity and traceability of the internal standard; and system cleanliness in the sample runs, where carryover or column degradation silently erode information quality over time.

By providing internal-standard-included kits alongside unspiked solutions and neat internal standards sold separately, AnalytiChem is aligning the range to serve two distinct lab workflows: those wanting fast, pre-configured services, and those with established technology who manage internal standard addition themselves.

Manufacturing and Traceability

The standards are produced at AnalytiChem's CONOSTAN Manufacturing Center, which holds ISO 17034 accreditation, the normal governing technology of reference materials.

"We developed our new CONOSTAN D3606 GC Standards range to give analysts complete confidence in their results at every stage of GC analysis for this key ASTM method," said Kimberly Halkiotis, Global Segment Leader Materials at AnalytiChem, in the announcement.

Context

CONOSTAN has been a recognized name in petroleum-sector reference standards for nearly five decades, with an existing portfolio spanning sulfur-in-petroleum standards, TAN, TBN, viscosity, and flashpoint CRMs. The D3606 range spreads that footprint into fuel-specific hydrocarbon speciation, a region where analysts have historically had to rely on standards sourced piecemeal or produced in-house.

According to Towards Healthcare, the North America biopharmaceutical process analytical technology market is projected to experience significant growth, with estimates suggesting the market size will increase from USD 2.57 billion in 2026 to approximately USD 6.85 billion by 2035, expanding at a CAGR of 11.53% from 2026 to 2035. Real-time product excellence assurance, minimized batch failure rates, limited manufacturing cycle times, lowered end-product testing, and seamless compliance with government standards are achieved via improved process understanding. Analytical technologies like spectroscopy and chromatography are broadly used in biotechnology research. Biopharmaceutical process analytical technology (PAT) is a regulatory and technical framework applied to design, analyze, and control production. It relies on real-time measurements of significant parameters to confirm product quality, reduce batch failures, and optimize manufacturing workflows without relying solely on delayed end-product testing. It is a science- and risk-based strategy for the design, monitoring, and control of manufacturing technology through real-time or near-real-time measurement of critical quality attributes (CQAs).

North America Biopharmaceutical Process Analytical Technology Market Size is USD 2.57 Billion in 2026

About AnalytiChem

AnalytiChem was formed through the acquisition and integration of organizations with expertise in specialized laboratory applications, bringing together decades of production experience and complementary product technologies. The organization focuses on supporting laboratories globally with specialized tools, reagents, and consumables intended to allow better measurements in analytical chemistry and microbiology, involving culture media, reference materials for inorganic and organic analysis, laboratory consumables, and sample preparation tools.

AnalytiChem employs over 600 people in the manufacturing, distribution, sales, and support centers in Europe, the United Kingdom, Canada, the United States, and Australia.

A recent report by Towards Healthcare highlights that the North America biopharmaceutical process analytical technology market is growing, as efficient analytical processes are essential for the successful advancement and commercialization of both small- and large-molecule drug substances and drug products. As the complexity of both biologic and chemical drug substances increases, analytical processes evolve as well. New analytical processes and methods are therefore significant to the fast-moving bio/pharma companies. Biopharmaceutical Process Analytical Technology (PAT) allows real-time monitoring and control of significant production variables.

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