Date : 06 April 2026

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| Companies | Headquarters | AI in Spine Surgery |
| Medtronic | Dublin, Ireland | AiBLE Ecosystem |
| Stryker | Kalamazoo, U.S. | Mako SmartRobotics |
| Zimmer Biomet | Warsaw, U.S. | ROSA One Spine |
| Johnson & Johnson (DePuy Synthes) | New Brunswick, U.S. | VELYS Spine |
| Globus Medical | Audubon, U.S. | ExcelsiusGPS |
| NuVasive | San Diego, U.S. | Pulse platform |
| Alphatec (ATEC) | Carlsbad, U.S. | EOS insight |
| Augmedics | Chicago, U.S. | xvision Spine System |
| Proprio | Seattle, U.S. | Paradigm |
| Brainlab | Munich, Germany | Elements Spine Planning |
In February 2026, the Stealth AXiS robotic system for spine surgery, developed by Medtronic, offering robotics, planning, and navigation, was announced to have received FDA clearance.
In September 2025, the Spine Mixed Reality Navigation, an advanced surgical navigation solution developed by Brainlab, providing mixed reality support, an ergonomic view of the navigation screen, and supporting surgeons to place pedicle screws directly in their field of view with the vital information, was announced to have received U.S. FDA 510(k) clearance.
The global AI in spine surgery market size was estimated at USD 1.85 billion in 2025 and is predicted to increase from USD 2.25 billion in 2026 to approximately USD 13.29 billion by 2035, expanding at a CAGR of 21.8% from 2026 to 2035.

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