Date : 31 March 2026

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| Company | Headquarters | Latest Update |
| Perrigo Company plc | Ireland | Perrigo organization is a leading provider of Consumer Self-Care Products and over-the-counter (OTC) health and wellness solutions that improve patients' well-being by empowering consumers to proactively prevent or treat conditions that are self-managed. |
| Galderma S.A | Switzerland | Galderma continues to strengthen its leadership in acne treatment, focusing on its established selection. |
| Teva Pharmaceutical Industries Ltd | Israel | Teva Pharmaceutical Industries Ltd. continues to provide generic Adapalene 0.1% Gel as part of its expansive dermatology portfolio. |
| Glenmark Pharmaceuticals Ltd | United States | In November 2025, Glenmark Pharmaceuticals, also with Dublin-based Cosmo Pharmaceuticals N.V., received conventional market authorisation (MA) from the European Commission (EC)for an acne management cream in 15 European countries. |
| Sun Pharmaceutical Industries Ltd | India | Sun Pharmaceutical Ind. Ltd. offers a broad range of active pharmaceutical ingredients, which includes adapalene. It belongs to the retinoid agent calming category. |
| Dr. Reddy’s Laboratories Ltd | India | This organization is actively increasing its dermatology and over-the-counter (OTC) portfolios. |
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The global adapalene market size was estimated at USD 611.1 million in 2025 and is predicted to increase from USD 635.18 million in 2026 to approximately USD 899.37 million by 2035, expanding at a CAGR of 3.94% from 2026 to 2035.

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